| 摘要 |
<p>A mixture of beads of uniform size is deposited in an array by establishing discrete alignment areas each consisting of a droplet of adhesive or small area of continuous adhesive layer exposed through an aperture in a mask. Beads which are trapped by the attachment areas are released by either a solvent on a vacuum manifold, or by evaporation of the adhesive, preferably by means of a vacuum centrifuge. The beads are released into capillaries, in which cleavage of attached compounds, or synthesis of new compounds, can be carried out. An apparatus used for carrying out the invention is shown in the figure, which comprises a mask (10) with side walls, an adhesive-coated film (12), a capillary array (16), a gasket (17), and a chemically resistant well plate (18).</p> |
