Erythromycin derivatives, their preparation process and their use as medicaments.

摘要

Erythromycin derivatives of formula (I) and their acid addition salts are new. X = CH2, SO2 or O; Y = (CH2)m(CH=CH)n(CH2)o; m+n+o is /~ 8 and n = 0 or 1; Ar = optionally substituted aryl; W = H or C(O)NHR''; R'' = 1-8C alkyl, or optionally substituted aryl; and Z = H or an acid residue.