| 摘要 |
Use of a compound comprising one or more * small Greek alpha *-amino acid residues of general formula (I), wherein R is selected from the group consisting of hydrogen, optionally substituted C 1 -C 20 alkyl, C 1 -C 20 alkenyl, aryl and aralkyl groups and a group R 5 -OCO- where R 5 is selected from C 1 -C 20 , C 1 -C 20 alkenyl, aryl and aralkyl groups; R 1 and R 2 are independently selected from the group consisting of hydrogen and optionally substituted C 1 -C 6 alkyl, C 1 -C 6 alkenyl, C 7 -C 12 arylalkyl and aryl groups; or R 1 and R 2 together represent a group -CR 6 R 7 , wherein R 6 and R 7 are independently selected from hydrogen, halogen, and optionally substituted C 1 -C 6 alkyl and aryl groups; wherein the compound does not contain free thiol groups; or a pharmaceutically acceptable salt thereof in the preparation of a medicament suitable for the treatment of a disease state caused by production of free radical species or in which free radical species are produced is provided, together with formulations and methods for their preparation.
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