发明名称 |
HIDTIL UKENDT ANTI-DR5-ANTISTOF |
摘要 |
The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies. |
申请公布号 |
DK2636736(T3) |
申请公布日期 |
2016.07.04 |
申请号 |
DK20110836421T |
申请日期 |
2011.10.27 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
OHTSUKA, Toshiaki;TAKIZAWA, Takeshi;OGUNI, Akiko;MATSUOKA, Tatsuji;YOSHIDA, Hiroko;MATSUI, Yumi |
分类号 |
C12N15/09;A61K31/337;A61K31/439;A61K31/4545;A61K31/4745;A61K31/475;A61K31/513;A61K31/555;A61K39/00;A61K39/395;A61P35/00;A61P43/00;C07K14/705;C07K16/28;C07K16/30;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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