发明名称 |
Radiolabeled o-methyl phosphotriester and o-methyl phosphorothioate internucleoside linkages and oligonucleotides containing the same |
摘要 |
The invention provides oligonucleotides containing methyl phosphotriester linkages and processes for making and methods for using such oligonucleotides. The preparation of radiolabeled oligonucleotides is also disclosed. The radiolabel is a 14C-methyl group attached to an oxygen atom of an internucleoside phosphate group. |
申请公布号 |
AU4049397(A) |
申请公布日期 |
1998.02.25 |
申请号 |
AU19970040493 |
申请日期 |
1997.08.01 |
申请人 |
HYBRIDON, INC. |
发明人 |
RADHAKRISHNAN P IYER;THERESA DEVLIN;IVAN HABUS;DONG YU;SUDHIR AGRAWAL;SUZANNE M. JOHNSON |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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