| 摘要 |
The present invention provides a new compound which shows slow and continuous blood pressure reducing action and is useful as an antihypertensive agent. The invention resides in a quinazoline derivative of the following formula (I) and its pharmaceutically acceptable salt: <CHEM> in which, each of R<1> and R<2> is H or an alkyl group of 1 to 6 carbon atoms, or R<1> and R<2> are combined to form an ethylene group; each of R<3> and R<4> is an alkyl group of 1 to 6 carbon atoms; R<5> is a hydrogen atom, a hydroxyl group, an alkyl group of 1 to 6 carbon atoms, or an alkoxy group of 1 to 6 carbon atoms; each of R<6> and R<7> is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms; and n is 2 or 3. The invention further resides in an antihypertensive agent containing the above compound. |
