| 摘要 |
PROBLEM TO BE SOLVED: To easily obtain the subject compound having antiinflammatory, analgesic and antipyretic actions and useful as pharmaceuticals on an industrial scale at a low cost by the hydrogenative decomposition of a specific mandelic acid derivative. SOLUTION: The objective compound of the formula II useful as pharmaceuticals can be produced by the hydrogenative decomposition of a mandelic acid derivative of the formula I [R<1> to R<3> are each H, a halogen, a 1-5C alkyl, a 1-5C alkoxy, OH or a (substituted)phenyl] (e.g. mandelic acid) in an organic solvent in the presence of a hydrogenative decomposition catalyst such as palladium or platinum. |
