The present invention relates to a re-useable limb protector for use in protecting a limb with a cast or bandage. The limb protector is comprised of stretchable moisture impervious material which is adjustable in size to accommodate a wide range of individuals. The limb protector is constructed to be readily adaptable to either right- or left-handed individuals and is molded of a single piece of skid retardant material. The water tight seal is accomplished by stretching the moisture impervious base unit and is locked in place by the folding over of the two locking straps. The invention of a reuseable limb protector which does not require the use of an encircling mechanism to acheive a water tight seal is designed herein to allow for a normal blood flow when a water tight seal is acheived. The open end of the base unit is designed to be of a sufficient diameter to prevent irritation to sensitive finger and toe areas which would be caused by a need to stretch open the base unit for insertion of a limb.