发明名称 |
HETEROCYCLIC COMPOUNDS |
摘要 |
There is disclosed a heterocyclic compound represented by general formula: (See Fig. I) wherein R1 represents hydrogen, lower alkyl or aryl; R2 represents hydrogen, hydroxyl or lower alkyl; A represents CH or N; X represents -O- or -NH-; R3 represents hydrogen, hydroxyl or lower alkyl; R4 represents lower alkyl; and n represents 0 or 1, or a pharmaceutically acceptable salt thereof. The compound and pharmaceutically acceptable salt are useful as antiemetics and suppressant of migraine.
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申请公布号 |
CA2043071(C) |
申请公布日期 |
1998.02.24 |
申请号 |
CA19912043071 |
申请日期 |
1991.05.23 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
SUZUKI, FUMIO;ICHIKAWA, SHUNJI;MIKI, ICHIRO;HAYASHI, HIROAKI;ISHII, AKIO;MIWA, YOSHIKAZU |
分类号 |
A61K31/435;A61K31/4375;A61K31/46;A61K31/47;A61K31/4704;A61P1/08;A61P25/04;A61P25/06;A61P25/18;A61P25/20;A61P25/22;A61P43/00;C07D451/04;C07D451/12;C07D451/14;C07D519/00;(IPC1-7):C07D451/04 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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