发明名称 PRODUCTION (I) OF TAXANE COMPOUNDS
摘要 PROBLEM TO BE SOLVED: To provide a method for producing taxane compounds having antitumor activities by which the productivity of the taxane compounds is extremely improved. SOLUTION: The objective taxane compounds are produced by culturing a cell capable of producing the taxane compounds derived from Taxus sp. in a culturing medium containing an added carbohydrate, subjecting the cell to produce the taxane compounds and collecting the taxane compounds from the cultured material. The cell-culturing is performed by inducing the cell in a solid culturing medium and culturing the multiplied callus by using the liquid culturing medium with the added carbohydrate. Fructose, maltose, lactose, raffinose, etc., are suitable for the carbohydrate.
申请公布号 JPH1052294(A) 申请公布日期 1998.02.24
申请号 JP19960227479 申请日期 1996.08.09
申请人 NIPPON OIL CO LTD 发明人 MORITA EITARO;MIZUTA YOSHINORI
分类号 C12P17/02;A61K36/00;A61P35/00;C07D305/14;C12N5/00;C12N5/04;C12R1/91 主分类号 C12P17/02
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