DNA encoding a growth factor specific for epithelial cells
摘要
Discoveries are disclosed that show particular aspect or recombinant DNA technology can be used successfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional forms from spontaneously secreting cells or from DNA segments introduced into cells. These forms variously enable biochemical and functional studies of this novel protein as well as product of antibodies. Means are described fro determining the level of expression of genes for the KGF protein, for example by measuring mRNA levels in cells or by measuring antigen secreted in extracellular or body fluids.
申请公布号
SG46699(A1)
申请公布日期
1998.02.20
申请号
SG19960008633
申请日期
1990.01.30
申请人
RUBIN, JEFFREY, S.;FINCH, PAUL, W.;AARONSON, STUART, A.
发明人
RUBIN, JEFFREY, S.;FINCH, PAUL, W.;AARONSON, STUART, A.