HEXAHYDRONAPHTHALENE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITION

摘要

FIELD: organic chemistry. SUBSTANCE: products: hexCHF>2@ means ethyl group; R means alkyl grahydronaphthalene ester compounds of the formula (I): where R means group of the formula (II) or (II) ; R means hydrogen atom; R means hydroxy-group; R means hydrogen atom or hydroxy-protective group, and/or (A) R means ethyl group; R means alkyl group having 1-4 carbon atoms or alkenyl group having 2-6 carbon atoms, and R means alkyl group having 2-4 carbon atoms or alkenyl group having 2-5 carbon atoms; or (b) R means propyl group; R means hydrogen atom, and R means propyl group; or (c) R means butyl group; R means methyl group, and R means methyl group, and its pharmaceutically acceptable salts. 2. Compound as at point 1 where: R means ethyl group; R means alkyl group having 1-4 carbon atoms or allyl group; and R means alkyl group having 2-4 carbon atoms or allyl group. 3. Compound as points 1 or 2 where: R means group of the formula (II) . 4. Compound as at point 3 where R means hydrogen atom. 5. Compound as at point 1 where: R as an active component and pharmaceutically acceptable carrier. EFFECT: improved method of synthesis. 9 cl, 10 tbl