| 摘要 |
FIELD: chemistry of peptides, medicine. SUBSTANCE: invention proposes (1R, 4aR, 8aR)-1,2,3,4,5,6,7,8-perhydroisoquinoline-1-carbonyl-(L)-arginine aldehyde and its pharmaceutically acceptable salts and solvates, pharmaceutical preparations containing above indicated compounds. Invention relates to methods of use of these compounds as thrombin inhibitors, coagulation inhibitors and preparations used for thrombosis treatment. EFFECT: enhanced effectiveness of agent proposed. 4 cl, 1 tbld |
