METHODS FOR REMOVING UNREACTED ELECTROPHILES FROM A REACTION MIXTURE
摘要
Simple and efficient methods of scavenging excess electrophiles from a reaction mixture are provided utilizing addition of water soluble nucleophiles or solid support bound nucleophiles. Resulting addition products are removed from reaction mixtures through convenient separation techniques.
申请公布号
WO9806671(A1)
申请公布日期
1998.02.19
申请号
WO1997US14281
申请日期
1997.08.13
申请人
ISIS PHARMACEUTICALS, INC.;JUNG, MICHAEL, E.;COOK, PHILLIP, DAN;KAWASAKI, ANDREW, M.
发明人
JUNG, MICHAEL, E.;COOK, PHILLIP, DAN;KAWASAKI, ANDREW, M.