NEURAMINIC ACID COMPOUNDS

摘要

Constitution: Neuraminic acid compounds represented by general formula (1) or pharmacologically acceptable salts thereof, wherein R<1> represents an optionally halogenated C1-C4 group; R<2>, R<3> and R<4> represent each independently hydrogen or C3-C25 aliphatic acyl; and W represents hydrogen or an ester residue, provided the case where R<1> represents methyl and each of R<2>, R<3>, R<4> and W represents hydrogen is excluded. Effect: These compounds are excellent in the sialidase inhibitory activity in vivo and so are useful as a remedy or preventive for influenza virus infections.