Compounds having a guanidine structure and pharmaceutical composition containing same

摘要

Guanidine derivatives are provided useful for promoting growth, repair and regeneration of a neuronal axon and for treating neuropathies and myopathies. The compounds have the formula: <IMAGE> I wherein R1 is an isopropyl radical, a benzyl radical which is optionally substituted by one or more (C1-C6)alkoxy radicals or a radical: <IMAGE> R2, R3 and R4 together with the nitrogen atoms to which they are attached and the carbon atom to which the said nitrogen atoms are attached form a pyrimidine ring of formula II or a pyrimidinium ring of formula IIa: <IMAGE> II <IMAGE> IIa