| 摘要 |
PCT No. PCT/EP95/02649 Sec. 371 Date May 31, 1996 Sec. 102(e) Date May 31, 1996 PCT Filed Jul. 7, 1995 PCT Pub. No. WO96/03422 PCT Pub. Date Feb. 8, 1996The present invention provides compounds of formula (D wherein the symbol +E,uns - - -+EE represents a single or a double bond; R is a hydrogen atom or a C1-C4 alkyl group; A is a single bond or a straight or branched C1-C6 alkylene chain; B is a straight or branched C1-C12 alkylene group optionally substituted by one or more aryl groups or fluorine atoms; W is a group R1 or (a) wherein R1 is a straight or branched C-C6 alkyl group unsubstituted or substituted by one or more fluorine atoms, provided that at least a fluorine atom is present in B or W. The compounds of the invention are useful as testosterone 5 alpha -reductase inhibitors.
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