发明名称 |
Method for the treatment of sclerosis of the glomeruli |
摘要 |
This invention relates to prophylactic or therapeutic drug for diabetic nephropathy or glomerulonephritis, comprising, as an active ingredient, a compound or salt thereof represented by general formula (I) <IMAGE> (I) wherein R1 stands for H or an optionally substituted hydrocarbon residue; R2 stands for an optionally esterified carboxyl group; R3 stands for a group actually or potentially capable of forming an anion; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic chain length of two or less; n stands for 1 or 2; ring A stands for a benzene ring having an optional substituent in addition to R2; Y stands for a bond, -O-, -S(O)m- (wherein m stands for 0, 1 or 2), or -N(R4)- (wherein R4 stands for H or an optionally substituted alkyl group).
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申请公布号 |
US5719173(A) |
申请公布日期 |
1998.02.17 |
申请号 |
US19960696475 |
申请日期 |
1996.08.14 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
NISHIKAWA, KOHEI;SHIBOUTA, YUMIKO;KUBO, KEIJI |
分类号 |
A61K31/415;A61K31/4184;A61K31/4245;A61P3/08;A61P3/10;A61P13/02;A61P15/00;A61P29/00;C07D403/10;C07D413/10;C07D417/10;(IPC1-7):A61K31/41 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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