发明名称 Method for the treatment of sclerosis of the glomeruli
摘要 This invention relates to prophylactic or therapeutic drug for diabetic nephropathy or glomerulonephritis, comprising, as an active ingredient, a compound or salt thereof represented by general formula (I) <IMAGE> (I) wherein R1 stands for H or an optionally substituted hydrocarbon residue; R2 stands for an optionally esterified carboxyl group; R3 stands for a group actually or potentially capable of forming an anion; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic chain length of two or less; n stands for 1 or 2; ring A stands for a benzene ring having an optional substituent in addition to R2; Y stands for a bond, -O-, -S(O)m- (wherein m stands for 0, 1 or 2), or -N(R4)- (wherein R4 stands for H or an optionally substituted alkyl group).
申请公布号 US5719173(A) 申请公布日期 1998.02.17
申请号 US19960696475 申请日期 1996.08.14
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 NISHIKAWA, KOHEI;SHIBOUTA, YUMIKO;KUBO, KEIJI
分类号 A61K31/415;A61K31/4184;A61K31/4245;A61P3/08;A61P3/10;A61P13/02;A61P15/00;A61P29/00;C07D403/10;C07D413/10;C07D417/10;(IPC1-7):A61K31/41 主分类号 A61K31/415
代理机构 代理人
主权项
地址