发明名称 |
2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives |
摘要 |
A process of preparing a 6-O-methyl erythromycin A derivative using a 2'-protected, 9-etheroxime erythromycin A intermediate is provided. A preferred protecting group for the 2'-position is acetyl. 2'-protected, 9-etheroxime erythromycin A derivatives are also provided. Also disclosed is a method for inhibiting quaternary salt formation at the 3' amine without the need for 3'N-protecting groups.
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申请公布号 |
US5719272(A) |
申请公布日期 |
1998.02.17 |
申请号 |
US19960627795 |
申请日期 |
1996.04.02 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
YANG, CHENGXI;PATEL, HEMANTKUMAR H.;KU, YI-YIN;LIU, JIH-HUA |
分类号 |
C07H17/08;(IPC1-7):C07H1/00 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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