METHOD FOR GRAFTING A SUBSTITUTED DIFLUOROMETHYLE GROUP

摘要

The invention concerns a method for grafting a substituted difluoromethyle group on a compound containing at least one electrophilic function, comprising the following steps: i) bringing said compound containing at least one electrophilic function in the presence of one nucleophilic reagent containing: a) a fluorocarboxylic acid of formula Ea - CF2 - COOH in which Ea represents an electroattracting atom or group, at least partly salified by one organic or mineral cation, and b) a polar aprotic solvent; and ii) exposing the reaction medium to the action of micro-waves. This method is used for forming in particular sulphinic or fluorine-containing sulphonic acids.