发明名称 AZABICYCLIC CARBAMOYLOXY MUTILIN DERIVATIVES FOR ANTIBACTERIAL USE
摘要 Compounds of formula (3), and pharmaceutically acceptable salts and derivatives thereof, in which R1 is vinyl or ethyl; and R2 is a group R3, R4CH2-, or R5R6C=CH-; wherein each of R3 and R4 is an azabicyclic ring system or R5 and R6 together with the carbon atom to which they are attached form an azabicyclic ring system, are useful in the prevention and treatment of microbial infections.
申请公布号 CA2262460(A1) 申请公布日期 1998.02.12
申请号 CA19972262460 申请日期 1997.07.29
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 HUNT, ERIC;TAKLE, ANDREW KENNETH;NAYLOR, ANTOINETTE
分类号 C07D487/08;A61K31/395;A61K31/407;A61K31/435;A61K31/4375;A61K31/439;A61P31/00;C07C271/32;C07C271/36;C07C271/64;C07C271/66;C07C281/02;C07C307/06;C07C311/08;C07C311/39;C07C311/53;C07C317/44;C07C323/60;C07C331/14;C07D203/08;C07D203/20;C07D207/16;C07D209/08;C07D211/62;C07D213/40;C07D213/70;C07D213/75;C07D213/80;C07D213/81;C07D213/82;C07D231/14;C07D239/38;C07D249/04;C07D249/10;C07D257/04;C07D261/18;C07D271/10;C07D271/113;C07D277/36;C07D277/80;C07D285/06;C07D285/12;C07D285/125;C07D295/092;C07D295/205;C07D295/215;C07D307/10;C07D307/66;C07D307/68;C07D317/66;C07D333/34;C07D333/38;C07D401/06;C07D417/06;C07D451/02;C07D453/02;C07D455/02;C07D471/08;C07D513/04;C07H15/24;(IPC1-7):C07D453/02 主分类号 C07D487/08
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