SUSTAINED RELEASE PREPARATIONS FOR INJECTION CONTAINING GABEXATE MESYLATE

摘要

Sustained release preparations for injection characterized by containing medicinally active ingredients, fibrinogen, blood-coagulation factor 13 thrombin and gabexate mesylate; and kits for preparing the same at the time of use. When processed into aqueous solutions for injection, these preparations do not immediately coagulate at room temperature. After injection, they rapidly gel or solidify in vivo and thus form fibrin clots followed by the sustained release of the drugs encapsulated therein. Thus, these preparations are fibrin clot forming agents which can be easily injected without requiring any special technique.