发明名称 |
Diagnostic test for Pseudomonas aeruginosa infections |
摘要 |
Methods and reagents are provided for a novel immunodiagnostic test for the presence of P. aeruginosa in a biological sample. Monoclonal antibodies are employed which bind to an outer membrane protein antigen, which may be exposed by a solubilizing reagent. The antibody binds substantially all strains of P. aeruginosa. No cross-reactivity with other species of Pseudomonas or with other clinically significant gram-negative or gram-positive species is observed. Conjugating the monoclonal antibody of the invention with a fluorescent label provides for a rapid and sensitive direct immunofluorescent test for P. aeruginosa.
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申请公布号 |
US5716829(A) |
申请公布日期 |
1998.02.10 |
申请号 |
US19950452845 |
申请日期 |
1995.05.30 |
申请人 |
GENETIC SYSTEMS CORPORATION |
发明人 |
ROSOK, MAE JOANNE;LOSTROM, MARK E.;DARVEAU, RICHARD P. |
分类号 |
G01N33/569;(IPC1-7):G01N33/569 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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地址 |
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