发明名称 |
G-protein coupled receptor hnfds78 |
摘要 |
Human G-Protein Coupled Receptor HNFDS78 polypeptides and DNA (RNA) encoding such G-Protein Coupled Receptor HNFDS78 and a procedure for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing such G-Protein Coupled Receptor HNFDS78 for the treatment of diseases, such as atherosclerosis, inflammatory disease, and infectious disease. Antagonists against such G-Protein Coupled Receptor HNFDS78 and their use as a therapeutic to treat disease are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding G-protein coupled receptors and for detecting altered levels of the polypeptide in a host. |
申请公布号 |
AU6649196(A) |
申请公布日期 |
1998.02.10 |
申请号 |
AU19960066491 |
申请日期 |
1996.07.22 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
DERK J. BERGSMA;NABIL A. ELSHOURBAGY;HENRY SARAU;STEVEN M RUBEN |
分类号 |
G01N33/53;A61K31/00;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/00;A61P13/08;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/18;A61P37/00;A61P37/08;A61P43/00;C07K14/705;C07K16/28;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;C12R1/19;C12R1/91;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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