发明名称 Multilayer enzyme electrode membranes and methods of making same
摘要 An electrochemical sensor is designed for use in detecting a concentration of an analyte in a sample solution. The sensor to have a longer useful lifetime, improved stability and improved response time for single or multiple use applications. In one aspect, some of these goals are achieved by providing the multilayer enzyme electrode membrane having both nonporous and microporous layers. The microporous layer is formed from a polymer binder, a polymer powder, a surfactant and a mineral powder. In another aspect, certain of these goals are achieved by the use of a layer comprised of an enzyme disposed within a polymer matrix. In certain embodiments, the multilayer enzyme electrode membrane includes an outermost layer which is capable of dissolving in the sample solution such that the interface between the multilayer enzyme electrode membrane and the sample solution is continually renewed. The sensor provides an electrical current output proportional to the reagent chemical interaction of the analyte with an immobilized enzyme layer during exposure of the sensor in such solution.
申请公布号 AU3270797(A) 申请公布日期 1998.02.09
申请号 AU19970032707 申请日期 1997.07.11
申请人 CHIRON DIAGNOSTICS CORPORATION 发明人 ROBERT MCCAFFREY;BONNIE DALZELL;KATARINA TKACIK;SUSAN HOLBERT;MARK BODEN;JAMES FLAHERTY;MICHAEL FLANAGAN;JOSEF BROWN;KIMIYA TAKESHITA;PETER EDELMAN
分类号 G01N27/327;C12Q1/00 主分类号 G01N27/327
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