发明名称 |
Diuretic compound |
摘要 |
A diuretic compound of Formula I <IMAGE> or pharmaceutically acceptable salt thereof where R1 is a C1-6 alkyl; R2 is halogen, C1-4 alkyl; and R3 is C1-4 alkoxy are disclosed, preferably, benzamide, 3-chloro-N-(2-ethyl-2-(3-methoxyphenyl)-4-(1-piperidinyl)butyl), monohydrochloride. The compounds are effective diuretics which increase the excretion of water with little increase in electrolyte excretion.
|
申请公布号 |
US5716970(A) |
申请公布日期 |
1998.02.10 |
申请号 |
US19950468129 |
申请日期 |
1995.06.06 |
申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
HUMPHREY, STEPHEN J.;CURRY, JAMES T.;JACOBSEN, E. JON |
分类号 |
C07D295/12;A61K31/445;A61P7/10;A61P43/00;C07D295/13;(IPC1-7):A61K31/445 |
主分类号 |
C07D295/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|