THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS

摘要

A thiazole compound of formula (I), wherein T is lower alkylene; u is 0 or 1; R<1> and R<2> are the same or different and are each H, or lower alkyl, etc.; R<3> is (1) or (2); R<4> is H or lower alkanoyloxy-lower alkyl, which shows inhibitory activity or protein kinase C(PKC, Ca<2+>/phospholipid-depending serine/threonine protein phosphatase), and are useful as a protein kinase C inhibitor.