PROTEINS, IN PARTICULAR MEMBRANE PROTEINS, OF HELICOBACTER PYLORI, THEIR PREPARATION AND USE

摘要

The present invention relates to novel proteins, in particular membrane proteins or proteins which are firmly associated with the membrane, which are derived from Helicobacter pylori (H. pylori) and which contain one of the peptide sequences selected from SEQ ID NO: 1, 2, 3, 6, 10, 11, 12, 14, 15, 16, 17, 18 or 19 according to Tables 1a-1c, or to parts or homologues thereof having a minimum length of five amino acids, and to their preparation and use as pharmaceutical compositions, in particular as vaccines, or as a diagnostic agent. Based on these data, genes coding for these and related proteins were also isolated as shown in SEQ ID NOS: 20, 21, 22, 23, 24, 25, 26 and 27.