| 发明名称 |
ARTIFICAL CHROMOSOMES, USES THEREOF AND METHODS FOR PREPARING ARTIFICIAL CHROMOSOMES |
| 摘要 |
Methods for preparing cell lines that contain artificial chromosomes, methods for preparation of artificial chromosomes, methods for purification of artificial chromosomes, methods for targeted insertion of heterologous DNA into artificial chromosomes, methods for amplification of nucleic acids and methods for delivery of the chromosomes to selected cells and tissues are provided. Also provided are cell lines for use in the methods, and cell lines and chromosomes produced by the methods. Methods for use of the artificial chromosomes are also provided. |
| 申请公布号 |
WO9740183(A3) |
申请公布日期 |
1998.02.05 |
| 申请号 |
WO1997US05911 |
申请日期 |
1997.04.10 |
| 申请人 |
THE BIOLOGICAL RESEARCH CENTER OF THE HUNGARIAN AC;LOMA LINDA UNIVERSITY;AMERICAN GENE THERAPY, INC.;HADLACZKY, GYULA;SZALAY, ALADAR, A. |
发明人 |
HADLACZKY, GYULA;SZALAY, ALADAR, A. |
| 分类号 |
A01H1/00;A01H5/00;A01K67/027;A61K38/00;A61K48/00;C12N5/10;C12N15/09;C12N15/113;C12N15/62;C12N15/82;C12N15/85 |
主分类号 |
A01H1/00 |
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