| 摘要 |
<p>This invention provides a method of contraception which comprises administering to a female of child-bearing age a combination of a progestin at a daily dosage of 40-500 mu g trimegestone, 250 mu g - 4 mg dienogest, or 250 mu g - 4 mg drospirenone, and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 mu g ethinyl estradiol for 23-25 days beginning on day 1 of the menstrual cycle; wherein the same dosage of the progestin and estrogen combination is administered in each of the 23-25 days, followed by the administration of an estrogen at a daily dosage equivalent in estrogenic activity to 5-15 mu g ethinyl estradiol for 3-5 days; wherein the same dosage of the estrogen is administered in each of the 3-5 days; such that the number of days of administration of the progestin and estrogen combination plus the number of days of administration of estrogen is equal to 28 per menstrual cycle.</p> |
