POLYNUCLEOTIDE AND ITS USE FOR MODULATING A DEFENCE RESPONSE IN PLANTS

摘要

The cloning of the Mlo gene of Barley, mlo mutants, and homologues from other species including rice and Arabidopsis thaliana enables manipulation of pathogen defence responses in plants. Nucleic acid and polypeptides are used in the production of transgenic plants in which the pathogen defence response is modulated, particularly stimulated. Various approaches enable diagnostic determination of the presence of susceptibility or resistance alleles in plants. Compounds able to modulate a defence response by interaction with Mlo or mlo protein are identifiable using assays involving the protein or fragments thereof.