发明名称 |
Azole compounds, their production and use. |
摘要 |
An azole compound represented by the formula (I): <CHEM> , wherein Ar is a substituted phenyl group; R<1> and R<2> independently are a hydrogen atom or a lower alkyl group, or R<1> and R<2> may combine together to form a lower alkylene group; R<3> is a group bonded through a carbon atom; R<4> is a hydrogen atom or an acyl group; X is a nitrogen atom or a methine group; and Y and Z independently are a nitrogen atom or a methine group which may optionally be substituted with a lower alkyl group, or a salt thereof, which is useful for prevention and therapy of fungal infections of mammals as antifungal agent. |
申请公布号 |
PH31082(A) |
申请公布日期 |
1998.02.05 |
申请号 |
PH19730000467 |
申请日期 |
1993.08.30 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
ITOH NATSUMI;OKONOGI MENJI;TAMURA NORIKAZU |
分类号 |
A61K31/41;A61K31/415;A61K31/44;A61K31/4427;A61K31/505;A61P31/04;A61P31/10;C07D233/70;C07D249/08;C07D249/12;C07D401/14;C07D403/06;C07D403/12;C07D521/00 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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