发明名称 METHOD FOR BONDING BIOLOGICALLY ACTIVE SUBSTANCES CONTAINING AMINO GROUP TO POLYSACCHARIDES
摘要 <p>The procedure described in this patent is based on that principle, that the polysaccharide in a form of H+ is suspended in dimethylformamide containing no water, it is cooled to he temperature of 0 Celsius degrees, the equimolar amount of triethyl amine and isobuthyl formiate is added, it is incubated for 15 up to 30 minutes, solution with biological activity, in molar ration 1 up to 1000 : 1, according to polysaccharide is added, and it is incubated. The substance with a biological activity is bound to polysaccharide via amidic bond, being able to be degraded in vivo.</p>
申请公布号 SK278783(B6) 申请公布日期 1998.02.04
申请号 SK19890007144 申请日期 1989.12.18
申请人 KERY VLADIMIR;NOVOTNY LADISLAV;TIHLARIK KAROL;SANDULA JOZEF;MASLER LADISLAV 发明人 KERY VLADIMIR;NOVOTNY LADISLAV;TIHLARIK KAROL;SANDULA JOZEF;MASLER LADISLAV
分类号 C08B37/00;A01N25/10;A61K47/36;C08F8/30;(IPC1-7):C08F8/30 主分类号 C08B37/00
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