发明名称 |
Immunoassay elements having a receptor zone |
摘要 |
A dry immunoassay analytical element, for assaying a ligand is disclosed. The element comprises, in the following order, (a) a layer containing a labeled ligand, (b) a bead spreading layer, c) a cross-linked hydrophilic polymer layer and d) a support; wherein (i) a fixed concentration of an immobilized receptor for the labeled ligand is located in a zone at the interface of layers (b) and (c); and (ii) the receptors are immobilized by being covalently bonded to polymeric beads that are smaller than the beads in layer (c).
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申请公布号 |
US5714340(A) |
申请公布日期 |
1998.02.03 |
申请号 |
US19940260939 |
申请日期 |
1994.06.16 |
申请人 |
JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. |
发明人 |
SUTTON, RICHARD CALVIN;SMITH-LEWIS, MARGARET JEANETTE;MAUCK, LINDA ANN;BOWMAN, WAYNE ARTHUR;DANIELSON, SUSAN JEAN |
分类号 |
G01N33/543;(IPC1-7):G01N33/53;G01N33/545 |
主分类号 |
G01N33/543 |
代理机构 |
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地址 |
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