发明名称 Novel proteins within the type e botulinum neurotoxin complex
摘要 The invention features a polypeptide complex synthesized by bacteria of the genus Clostridia that contains the serotype E botulinum neurotoxin and five neurotoxin associated polypeptides having molecular weights of about 118, 80, 65, 40, and 18kDa, respectively. The complex is useful in the treatment of diseases or conditions that are caused by excessive release of acetylcholine from presynaptic nerve terminals.
申请公布号 AU6636096(A) 申请公布日期 1998.02.02
申请号 AU19960066360 申请日期 1996.07.08
申请人 UNIVERSITY OF MASSACHUSETTS DARTMOUTH 发明人 BAL RAM SINGH;ZHONG ZHANG
分类号 A61K39/00;C07K14/33 主分类号 A61K39/00
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