PROCESS FOR THE PREPARATION OF CHIRAL INTERMEDIATES USEFUL FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS.

摘要

Described is a process for preparing chiral compounds of formula (II), wherein X1 and X2 are independently F or Cl, and Y is Cl, Br or I, comprising reacting a triol of formula (VIII), wherein X1 and X2 are as defined above, with acetone in the presence of a catalyst, then with a halogen selected from Cl2, Br2 or I2, or N-bromosuccinimide or N-iodosuccinimide.