| 发明名称 |
ENDOTHELIAL CELL-LEUKOCYTE ADHESION MOLECULES (ELAMs) AND MOLECULES INVOLVED IN LEUKOCYTE ADHESION (MILAs) |
| 摘要 |
<p>The invention relates to molecules involved in the adhesion of leukocytes to endothelial cells during inflammation and DNA sequences encoding them. In particular it refers to ELAMs, including ELAM1 and Vascular Adhesion Molecule 1 and 1b (VCAM1 and VCAM1b). It also relates to MILAs, such as CDX and VLA4.</p> |
| 申请公布号 |
EP0458911(B1) |
申请公布日期 |
1998.01.28 |
| 申请号 |
EP19900911366 |
申请日期 |
1990.04.27 |
| 申请人 |
BIOGEN, INC. |
发明人 |
HESSION, CATHERINE, A.;LOBB, ROY, R.;GOELZ, SUSAN, E.;OSBORN, LAURELEE;BENJAMIN, CHRISTOPHER, D.;ROSA, MARGARET, D. |
| 分类号 |
G01N33/50;A61K31/7105;A61K35/16;A61K38/00;A61K39/395;A61K45/00;A61K47/48;A61K48/00;A61K49/00;A61K51/00;A61P1/00;A61P17/00;A61P29/00;A61P35/00;C07H21/04;C07K7/00;C07K14/00;C07K14/195;C07K14/41;C07K14/435;C07K14/47;C07K14/705;C07K16/00;C07K16/18;C07K16/28;C07K16/42;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/00;C12N15/02;C12N15/04;C12N15/09;C12N15/113;C12N15/12;C12N15/62;C12N15/63;C12N15/70;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;C12R1/19;C12R1/91;G01N33/00;G01N33/15;G01N33/53;G01N33/536;G01N33/543;G01N33/566;G01N33/577;(IPC1-7):A61K31/70;C07K4/00;C07K2/00;C07K1/00;C07H15/12 |
主分类号 |
G01N33/50 |
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