Pharmaceutical compositions based on chewing gum and a method for the preparation thereof

摘要

PCT No. PCT/EP95/02816 Sec. 371 Date May 29, 1996 Sec. 102(e) Date May 29, 1996 PCT Filed Jul. 15, 1995 PCT Pub. No. WO96/03111 PCT Pub. Date Feb. 8, 1996Chewing gum tablets and their methods of preparation are disclosed. The gum tablets contain a mixture of chewing gum base and sugary microgranules with an additive agent and an active ingredient adsorbed onto their surface. A lacquer coating on the tablet contains cellulose and polyethlene glycols. The sugary microgranules are delayed release coated particles. The chewing gums act as vehicles for active ingredients. These active ingredients may be used alone or in combination in normal physical form in the form of coated microspheres.