发明名称 |
Pyrrolo-pyridine derivatives |
摘要 |
A class of pyrrolo[2,3 -b]pyridine derivatives, linked via the 3-position thereof by a methylene group to a tetrahydropyridinyl moiety, the latter moiety being substituted in turn by an aryl- or heteroaryl-substituted divalent monocyclic radical, are ligands for dopamine receptorsubtypes within the body, in particular the D4 subtype, and are accordingly of use in the treatment and/or prevention of disorders of the dopamine system, including schizophrenia and depression.
|
申请公布号 |
US5712285(A) |
申请公布日期 |
1998.01.27 |
申请号 |
US19960626099 |
申请日期 |
1996.04.03 |
申请人 |
MERCK, SHARP & DOHME, LTD. |
发明人 |
CURTIS, NEIL ROY;KULAGOWSKI, JANUSZ JOZEF;LEESON, PAUL DAVID;RIDGILL, MARK PETER |
分类号 |
C07D471/04;(IPC1-7):A61K31/435 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|