发明名称 SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES
摘要 The compounds of formula (I) wherein R1, R2, R3 and A are as defined herein are useful, via potassium channel modulation, in the treatment of disorders associated with smooth muscle contraction. Such disorders include, but are not limited to, urinary incontinence, hypertension, asthma, premature labor, irritable bowel syndrome, congestive heart failure, angina and cerebral vascular disease.
申请公布号 WO9802413(A1) 申请公布日期 1998.01.22
申请号 WO1997US11992 申请日期 1997.07.16
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 ANTANE, MADELENE, MIYOKO;HERBST, DAVID, RICHARD;MCFARLANE, GERALDINE, RUTH;GUNDERSEN, ERIC, GOULD;HIRTH, BRADFORD, HAMMOND;QUAGLIATO, DOMINICK, ANTHONY;GRACEFFA, RUSSELL, FRANCIS;BUTERA, JOHN, ANTHONY;GILBERT, ADAM, MATTHEW
分类号 A61K31/16;A61K31/165;A61K31/18;A61K31/27;A61K31/275;A61P9/12;C07C221/00;C07C225/20;C07C233/41;C07C255/58;C07C271/24 主分类号 A61K31/16
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