发明名称 |
USE OF IDEBENONE AND ANALOGUES AGAINST BETA AMYLOID INDUCED CYTOTOXICITY |
摘要 |
A compound of formula (I) or (II) wherein R1 represents a lower alkyl; R2 represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R3 and R4 each represents an optionally substituted lower alkyl or a lower alkoxy, or R3 and R4 form, taken together, an optionally substituted butadienylene; and X1 and X2 each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytotoxicity of .beta.-amyloid protein.
|
申请公布号 |
CA2252519(A1) |
申请公布日期 |
1998.01.22 |
申请号 |
CA19972252519 |
申请日期 |
1997.07.10 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
HIRAI, KEISUKE;GOTO, GIICHI;MIYAMOTO, MASAOMI |
分类号 |
A61K31/047;A61K31/122;(IPC1-7):A61K31/12;A61K31/075;A61K31/21;A61K31/33 |
主分类号 |
A61K31/047 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|