发明名称 |
Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping |
摘要 |
The present invention relates to novel methods for sequencing and mapping genetic markers in polynucleotide sequences using Type-IIs restriction endonucleases. The methods herein described result in the "capturing" and determination of specific oligonucleotide sequences located adjacent to Type-IIs restriction sites. The resulting sequences are useful as effective markers for use in genetic mapping, screening and manipulation.
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申请公布号 |
US5710000(A) |
申请公布日期 |
1998.01.20 |
申请号 |
US19950485606 |
申请日期 |
1995.06.07 |
申请人 |
AFFYMETRIX, INC. |
发明人 |
SAPOLSKY, RONALD J.;LIPSHUTZ, ROBERT J.;GINGERAS, THOMAS R. |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C12N15/09;C12N15/10 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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