发明名称 Method of extracting sennosides A, B and A1
摘要 Sennosides A, B and Al of the formula: <IMAGE> which are substantially free from sennosides C, D and Dl, and from aloe-emodin derivatives, are prepared by a process wherein a) a sennoside mixture is reduced to rhein-9-anthrone-8-glucoside and aloe-emodin-9-anthrone-8-glucoside, b) a liquid-liquid partitioning of the compounds obtained is carried out between a polar organic solvent which is only partly miscible with water and an aqueous phase and c) the rhein-9-anthrone-8-glycosides contained after the partitioning in the aqueous phase is again oxidized to the corresponding sennosides and these are recovered.
申请公布号 US5710260(A) 申请公布日期 1998.01.20
申请号 US19950614772 申请日期 1995.12.21
申请人 MADAUS AG 发明人 CARCASONA, ALFONS;GRIMMINGER, WOLF;HIETALA, PENTTI;ZAESKE, HELGA;WITTHOHN, KLAUS
分类号 C07H15/24;(IPC1-7):C07H15/244;C07H1/00;A61K35/78 主分类号 C07H15/24
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