发明名称 |
INDOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
摘要 |
FIELD: organic chemistry. SUBSTANCE: product: derivatives of indole of the formula (I): <EMI ID=0.71 HE=21 WI=66 TI=CHI> where W - <EMI ID=0.72 HE=15 WI=24 TI=CHI>; n = 1; m = 1; R<SB>1</SB> - H, C<SB>1</SB>-C<SB>8</SB>-alkyl, QR<SB>4</SB> where R<SB>4</SB> - CO-R<SB>9</SB> where R<SB>9</SB> - C<SB>1</SB>-C<SB>8</SB>-alkyl; Q - C<SB>1</SB>-C<SB>3</SB>-alkyl; R<SB>11</SB> - H, or their pharmaceutically acceptable salts. The synthesized compounds are agonists of sertonine (5-HT). EFFECT: improved method of synthesis. 21 cl, 1 tbl |
申请公布号 |
RU2101283(C1) |
申请公布日期 |
1998.01.10 |
申请号 |
RU19940045897 |
申请日期 |
1993.03.10 |
申请人 |
PFAJZER INK. |
发明人 |
DZHON I.MEHJKOR;MARTIN DZH.UITS;DZHON I.MEHJKOR;MARTIN DZH.UITS |
分类号 |
A61K31/40;A61K31/404;A61K31/41;A61P3/04;A61P9/08;A61P9/12;A61P25/04;A61P25/06;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07D207/08;C07D209/04;C07D263/08;C07D403/06;C07D403/14;C07D413/12;C07D413/14 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|