发明名称 Oral cyclosporin formulations.
摘要 Improved oral cyclosporin formulations which have high bioavailability and are capable of admiration in hard capsules are provided. In the subject formations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formalations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
申请公布号 ZA9701569(B) 申请公布日期 1998.01.08
申请号 ZA19970001569 申请日期 1997.02.24
申请人 SANGSTAT MEDICAL CORPORATION;UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 发明人 MOO J. CHO;RALPH E. LEVY;PHILIPPE J. POULETTY
分类号 A61K47/34;A61K9/10;A61K9/48;A61K31/13;A61K38/13;A61K47/10;A61K47/14;A61K47/26;A61P37/02;C02F1/50 主分类号 A61K47/34
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