发明名称 |
SERINE PROTEASE INHIBITORS |
摘要 |
Bifunctional serine protease inhibitors and methods of preparing boroncontaining peptides are provided. The serine protease inhiitors comprise a catalytic site-directed moiety, which binds to and inhibits the active site of a serine protease, and an exosite associating moiety, which are joined by a connector moiety. The catalytic site directed moiety and the exosite associating moiety are capable of binding simultaneously to a molecule of the serine protease.
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申请公布号 |
CA2258634(A1) |
申请公布日期 |
1998.01.08 |
申请号 |
CA19972258634 |
申请日期 |
1997.06.11 |
申请人 |
TRIGEN LIMITED |
发明人 |
SCULLY, MICHAEL FINBARR;KAKKAR, VIJAY VIR;GREEN, DONOVAN;ELGENDY, SAID;DEADMAN, JOHN JOSEPH;SKORDALAKES, EMMANUEL;GOODWIN, CHRISTOPHER ANDREW |
分类号 |
A61K38/55;A61K38/00;A61K38/58;A61P43/00;C07K1/10;C07K5/06;C07K5/065;C07K14/81;C07K14/815;(IPC1-7):C07K19/00;C07F5/04;C07K1/04;C12N9/64;C12N9/68;C12N9/96 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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