发明名称 Therapeutic treatment for cardiovascular diseases
摘要 A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N,N'-1,1'-((27''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)]-1(H)-pyrrole-2,5-dione hydrochloride salt.
申请公布号 AU3476397(A) 申请公布日期 1998.01.07
申请号 AU19970034763 申请日期 1997.06.12
申请人 ELI LILLY AND COMPANY 发明人 MICHAEL R. JIROUSEK;WILLIAM FRANCIS HEATH JR.;DOUGLAS KIRK WAYS;LAWRENCE E. STRAMM
分类号 C07D487/22;A61K31/00;A61K31/40;A61K31/407;A61P3/00;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P13/00;A61P43/00;C07C43/174;C07C43/178;C07D498/22;C07D513/22;C07F7/18 主分类号 C07D487/22
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