发明名称 |
Promiscuous g-protein compositions and their use |
摘要 |
Disclosed are compositions and methods for their use, such as in identifying G-protein coupled receptors and ligands and compounds that modulate signal transduction. The compositions and methods employ promicuous G-proteins. Activation of the promiscous G-protein can be detected in a variety of assays, including assays in which activation is indicated by a change in fluorescence emission of a sample that contains the composition. |
申请公布号 |
AU3572897(A) |
申请公布日期 |
1998.01.07 |
申请号 |
AU19970035728 |
申请日期 |
1997.06.20 |
申请人 |
AURORA BIOSCIENCES CORPORATION |
发明人 |
PAUL A. NEGULESCU;STEFAN OFFERMANNS;MELVIN SIMON;CHARLES ZUKER |
分类号 |
C07K14/705;C12N15/85;G01N33/50 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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