发明名称 |
PURIFIED SPERM SURFACE ANTIGEN, MONOCLONAL ANTIBODY THEREFORAND APPLICATIONS THEREFOR |
摘要 |
The monoclonal antibody (S19), expressed by Deposit HB 12144, ATCC, effectively agglutinates a sperm surface glycoprotein, SAGA-1 protein. The mAB finds utility as a binding agent in a spermicide, showing a high degree of effectiveness in binding potential sperm. The protein bound, identified as SAGA-1, is the immunogen in a contraceptive vaccine, as well as the standard for determining antibody titer upon vaccination. The monoclonal antibody can also be used as a diagnostic to determine the presence, and amount, of sperm in a variety of samples.
|
申请公布号 |
CA2258717(A1) |
申请公布日期 |
1998.01.08 |
申请号 |
CA19972258717 |
申请日期 |
1997.06.30 |
申请人 |
THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
HERR, JOHN C.;DIEKMAN, ALAN B.;NORTON, ELIZABETH;WESTBROOK-CASE, ANN |
分类号 |
G01N33/53;A61K39/00;A61K39/395;A61P15/18;A61P43/00;C07K14/705;C07K16/28;C12N15/02;C12P21/08;G01N33/577;(IPC1-7):C07K16/28;A61K9/127;G01N33/564 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|