Compositions and methods for treating specific gene expression-related diseases and disorders in humans

摘要

The present invention provides therapeutic compositions and methods for treating humans suffering from diseases or disorders caused by cellular expression of aberrant exogenous genes or aberrant endogenous genes comprising administering to the human a therapeutically effective amount of a composition of the invention comprising an oligonucleotide capable of specifically down-regulating the expression of such a gene. A specific example is given for the treatment of HIV infections.